HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28330616, 30344098
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 644
+	Hs
		905870 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516386 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516441 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516454 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Zm
		6224 B4FJL0_MAIZE (4-314): 0: 550: 75.24		A0A1D6E6L1_MAIZE (2-456): 6.76e-67: 232: 24.68
+	Sp
		532280 PP11_SCHPO (7-322): 0: 555: 82.92		PABP_SCHPO (2-414): 5.25e-64: 225: 25.12
+	Hs
		582100 PP1G_HUMAN (1-323): 0: 603: 100.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		582179 PP1A_HUMAN (1-323): 0: 579: 90.66		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		582180 PP1B_HUMAN (1-322): 0: 560: 86.89		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Mm
		857299 PP1B_MOUSE (1-322): 0: 560: 86.89		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12