Protein: SMC4
Structural maintenance of chromosomes protein 4

Gene: SMC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: Q12267

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000796 - condensin complex
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758766

SMC2
Structural maintenance of chromosomes protein 2

6

16

Small-scale

0.950

High

745528

CND2
Condensin complex subunit 2

6

7

Small-scale

0.938

High

986208

CND1
Condensin complex subunit 1

4

18

Small-scale

0.887

High

810789

SMC3
Structural maintenance of chromosomes protein 3

2

19

Small-scale

0.775

High

988669

CND3
Condensin complex subunit 3

6

10

Small-scale

0.729

High

339911

CDK1
Cyclin-dependent kinase 1

3

10

Small-scale

0.670

High

700811

SMC1
Structural maintenance of chromosomes protein 1

1

17

Small-scale

0.618

High

812452

NNF1
Kinetochore-associated protein NNF1

2

1

High-throughput

0.595

High

995839

SGO1
Shugoshin

2

3

Small-scale

0.595

High

636092

CSM1
Monopolin complex subunit CSM1

2

1

Small-scale

0.584

High

429789

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.536

High

992640

PML1
Pre-mRNA leakage protein 1

1

0

High-throughput

0.513

High

708079

NUF2
Kinetochore protein NUF2

1

4

High-throughput

0.508

High

361083

TBB
Tubulin beta chain

1

5

Small-scale

0.501

High

454503

TBA1
Tubulin alpha-1 chain

1

9

Small-scale

0.501

High

743206

BOB1
Protein BOB1

1

6

High-throughput

0.501

High

961523

CDC14
Tyrosine-protein phosphatase CDC14

1

9

Small-scale

0.501

High

800710

SCD6
Protein SCD6

1

1

Small-scale

0.481

High

431425

MOD5
tRNA dimethylallyltransferase

1

1

Small-scale

0.479

High

607361

RFA1
Replication factor A protein 1

1

4

Small-scale

0.479

High

663674

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

747756

SLI15
Inner centromere protein-related protein SLI15

1

1

Small-scale

0.479

High

812277

BIR1
Protein BIR1

1

1

Small-scale

0.479

High

866560

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

1015275

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

1015401

SMT3
Ubiquitin-like protein SMT3

1

7

High-throughput

0.479

High

1015402

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

860696

NNF2
Protein NNF2

1

1

High-throughput

0.464

High

689062

TFC1
Transcription factor tau 95 kDa subunit

1

0

Small-scale

0.458

High

367088

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

513208

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

695809

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

769803

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

812344

DPH4
Diphthamide biosynthesis protein 4

1

4

High-throughput

0.445

High

865511

JJJ1
J protein JJJ1

1

7

High-throughput

0.445

High

865948

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.445

High

992256

RIX7
Ribosome biogenesis ATPase RIX7

1

1

High-throughput

0.445

High

866201

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

378411

LEU3
3-isopropylmalate dehydrogenase

1

1

Small-scale

0.437

High

489683

MPPB
Mitochondrial-processing peptidase subunit beta

2

0

High-throughput

0.307

High

479641

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.249

Low

644832

RFA3
Replication factor A protein 3

1

0

Small-scale

0.249

Low

732988

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

859723

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024