Protein: AP1G1
AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin)

Gene: AP1G1, APL4
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: Q12028

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0030121 - AP-1 adaptor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778868

AP1B1
AP-1 complex subunit beta-1

10

16

Small-scale

0.979

High

763216

AP1S1
AP-1 complex subunit sigma-1

9

20

Small-scale

0.973

High

1027321

AP1M1
AP-1 complex subunit mu-1-I

6

20

Small-scale

0.947

High

802142

APM2
Adaptin medium chain homolog APM2

4

20

High-throughput

0.890

High

1084136

AP1G1
AP-1 complex subunit gamma-1

3

15

High-throughput

0.849

High

644854

CLH
Clathrin heavy chain

2

9

Small-scale

0.793

High

805313

GGA2
ADP-ribosylation factor-binding protein GGA2

1

12

High-throughput

0.698

High

812745

LAA1
AP-1 accessory protein LAA1

4

4

Small-scale

0.685

High

866178

ENT3
Epsin-3

3

20

Small-scale

0.670

High

1044014

ENT5
Epsin-5

3

20

Small-scale

0.658

High

536186

ARF1
ADP-ribosylation factor 1

1

20

Small-scale

0.647

High

527946

HSP72
Heat shock protein SSA2

2

11

High-throughput

0.571

High

580214

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.571

High

546639

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.552

High

555170

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.536

High

1084143

CMR1
DNA damage-binding protein CMR1

2

3

High-throughput

0.533

High

441289

KAPA
cAMP-dependent protein kinase type 1

1

4

High-throughput

0.501

High

1084140

VAM3
Syntaxin VAM3

1

3

Small-scale

0.501

High

850671

IRC6
Increased recombination centers protein 6

1

1

High-throughput

0.494

High

1084141

INP53
Polyphosphatidylinositol phosphatase INP53

1

14

High-throughput

0.494

High

722336

XPO1
Exportin-1

1

19

High-throughput

0.489

High

1036137

PVH1
Tyrosine-protein phosphatase YVH1

1

2

High-throughput

0.489

High

393490

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

435423

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

531922

RL4A
Large ribosomal subunit protein uL4A

1

4

High-throughput

0.479

High

781548

ALY1
Arrestin-related trafficking adapter 6

1

2

Small-scale

0.479

High

864277

ALY2
Arrestin-related trafficking adapter 3

1

6

Small-scale

0.479

High

874579

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

1033619

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

1044821

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

1059400

VAM6
Vacuolar morphogenesis protein 6

1

7

High-throughput

0.479

High

1084139

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

1084137

CHS5
Chitin biosynthesis protein CHS5

1

0

Small-scale

0.460

High

1084142

LDB19
Protein LDB19

1

0

Small-scale

0.460

High

849762

MIL1
Probable lipase MIL1

1

0

Small-scale

0.458

High

1046326

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

394990

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

439447

PDC1
Pyruvate decarboxylase isozyme 1

1

4

High-throughput

0.445

High

525458

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

592559

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

671222

SIS1
Protein SIS1

1

3

High-throughput

0.445

High

742619

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

820051

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

682417

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

708461

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

710031

BMH1
Protein BMH1

1

3

High-throughput

0.437

High

795258

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

809178

GAA1
GPI transamidase component GAA1

1

1

High-throughput

0.437

High

812298

ATC3
Phospholipid-transporting ATPase DRS2

1

1

Small-scale

0.437

High

932246

ORC1
Origin recognition complex subunit 1

1

8

High-throughput

0.437

High

963780

H3
Histone H3

1

2

High-throughput

0.437

High

1044498

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

1035182

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

358368

ADH1
Alcohol dehydrogenase 1

1

2

High-throughput

0.407

High

365218

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.407

High

810784

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.407

High

825489

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.407

High

836946

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

744797

LAA2
Clathrin adapter accessory protein LAA2

2

0

Small-scale

0.317

High

829812

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.279

Low

712824

CHS3
Chitin synthase 3

1

0

Small-scale

0.251

Low

764025

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

804877

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.249

Low

1064279

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

574940

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

797867

FTH1
Iron transporter FTH1

1

0

High-throughput

0.238

Low

1056589

VAC14
Vacuole morphology and inheritance protein 14

1

0

Small-scale

0.238

Low

1084138

SAS10
Something about silencing protein 10

1

0

High-throughput

0.238

Low

386902

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

486344

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025