Interactor 1: TGFR1 (P36897)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: TGFBR1
Interactor 2: MYOC (Q99972)
Myocilin (Myocilin 55 kDa subunit) (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)]
Gene: MYOC
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 0.55 | 0.460 |
The method score is based on:
Property | Details |
---|---|
Experiments | 16289162 |
Identification Methods | two hybrid |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0007165 - signal transduction GO:0030335 - positive regulation of cell migration GO:0046872 - metal ion binding GO:0051496 - positive regulation of stress fiber assembly GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
Homologous interactions | 0 |
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Last updated: 15 Jul 2024