HitPredict

Interactor 1: PUB1 (P32588)
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 (ARS consensus-binding protein ACBP-60) (Poly uridylate-binding protein) (Poly(U)-binding protein)
Gene: PUB1

Interactor 2: SGN1 (P40561)
RNA-binding protein SGN1
Gene: SGN1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	11805826, 11805837, 18467557, 32857852, 16429126
Identification Methods	tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 453 Sc			1 250
+	Sc
		403417 PUB1_YEAST (1-441): 1.75e-90: 283: 100.00		PABP_YEAST (34-152): 2.79e-19: 88.3: 22.50
+	Sc
		403543 PABP_YEAST (2-319): 6.07e-47: 172: 19.46		SGN1_YEAST (1-250): 4.4e-57: 184: 100.00
+	Sp
		153884 PABP_SCHPO (30-332): 1.6e-46: 172: 19.12		PAB2_SCHPO (1-147): 8.48e-37: 129: 31.76
+	Sc
		403283 PABP_YEAST (2-319): 6.07e-47: 172: 19.46		PABP_YEAST (34-152): 2.79e-19: 88.3: 22.50
+	Zm
		8282 A0A1D6ELH4_MAIZE (43-453): 2.16e-46: 172: 16.03		A0A1D6ELH4_MAIZE (40-152): 2.44e-18: 85.6: 18.42
+	At
		1372834 RB45B_ARATH (48-277): 3.17e-18: 88.2: 30.38		PABN1_ARATH (12-198): 5.78e-41: 141: 32.09
+	Hs
		550237 TIAR_HUMAN (75-253): 2.45e-30: 122: 41.08		PABP1_HUMAN (25-152): 1.6e-20: 92.1: 18.61
+	Hs
		550346 PABP1_HUMAN (6-167): 8.87e-17: 85: 15.85		PABP2_HUMAN (1-203): 2.8e-34: 126: 25.12
+	At
		1443603 RB45B_ARATH (48-277): 3.17e-18: 88.2: 30.38		PABN3_ARATH (2-199): 5.69e-32: 118: 28.79
+	Mm
		710979 TIA1_MOUSE (75-250): 2.54e-27: 114: 38.10		PABP1_MOUSE (25-152): 1.99e-20: 91.7: 18.61
+	Hs
		550137 TIA1_HUMAN (75-250): 8.12e-27: 112: 38.10		PABP1_HUMAN (25-152): 1.6e-20: 92.1: 18.61
+	Sc
		403620 NAM8_YEAST (76-310): 5.67e-22: 100: 16.11		PABP_YEAST (34-152): 2.79e-19: 88.3: 22.50
+	Hs
		550262 PABP4_HUMAN (6-167): 6.18e-18: 88.4: 14.72		PABP1_HUMAN (25-152): 1.6e-20: 92.1: 18.61
+	Hs
		1197178 PABP3_HUMAN (6-167): 6.62e-17: 85.3: 15.85		PAP1L_HUMAN (25-152): 1.54e-20: 92.1: 15.50
+	Hs
		550464 PABP3_HUMAN (6-167): 6.62e-17: 85.3: 15.85		PABP1_HUMAN (25-152): 1.6e-20: 92.1: 18.61
+	Hs
		550097 PABP1_HUMAN (6-167): 8.87e-17: 85: 15.85		PABP1_HUMAN (25-152): 1.6e-20: 92.1: 18.61
+	Hs
		550311 PABP1_HUMAN (6-167): 8.87e-17: 85: 15.85		PAP1L_HUMAN (25-152): 1.54e-20: 92.1: 15.50
+	Hs
		1102095 PABP4_HUMAN (6-167): 6.18e-18: 88.4: 14.72		PABP3_HUMAN (31-152): 3.49e-18: 85.2: 19.20