HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0043066 - negative regulation of apoptotic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 679
+	Rn
		741578 SYUA_RAT (1-140): 2.23e-57: 176: 95.00		HSP7C_RAT (51-653): 0: 883: 50.16
+	Hs
		503576 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		713917 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		HS71L_HUMAN (49-673): 0: 883: 47.59
+	Rn
		94362 SYUA_RAT (1-140): 2.23e-57: 176: 95.00		F1M953_RAT (1-679): 0: 863: 98.38
+	Hs
		501775 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		BIP_HUMAN (53-677): 0: 566: 50.55