HitPredict

Interactor 1: YPT10 (P38146)
GTP-binding protein YPT10
Gene: YPT10

Interactor 2: YPT6 (Q99260)
GTP-binding protein YPT6
Gene: YPT6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22157956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0012505 - endomembrane system
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 199 Sc			1 215
+	Hs
		894715 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAB8A_HUMAN (11-215): 2.51e-89: 263: 39.02
+	Zm
		73944 B4FAE1_MAIZE (2-198): 5.73e-81: 241: 25.62		B4FAE1_MAIZE (7-214): 5.54e-85: 252: 35.10
+	Hs
		918846 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAB1A_HUMAN (1-215): 1.85e-84: 250: 33.33
+	Hs
		845881 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAB13_HUMAN (1-214): 5.78e-85: 251: 37.85
+	Hs
		913992 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RB11A_HUMAN (1-214): 2.15e-83: 248: 32.09
+	Hs
		1273009 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAB8B_HUMAN (1-215): 6.15e-84: 249: 38.61
+	Hs
		918944 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAB1B_HUMAN (7-215): 7.88e-82: 244: 33.49
+	Hs
		896605 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAB14_HUMAN (1-215): 4.81e-81: 242: 30.88
+	Mm
		919000 RAB1A_MOUSE (2-198): 1.26e-80: 240: 27.59		RAB1B_MOUSE (7-215): 1.77e-81: 242: 33.97
+	Hs
		918879 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RB11B_HUMAN (1-214): 3.37e-80: 240: 30.42
+	Hs
		918916 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAB2B_HUMAN (7-214): 2.25e-80: 240: 32.41
+	Hs
		896681 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAB14_HUMAN (1-215): 4.81e-81: 242: 30.88
+	Hs
		1079964 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RB11B_HUMAN (1-214): 3.37e-80: 240: 30.42
+	Hs
		1259991 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAB2B_HUMAN (7-214): 2.25e-80: 240: 32.41
+	Sc
		731169 YPT10_YEAST (1-199): 1.14e-94: 275: 100.00		VPS21_YEAST (7-215): 9.74e-42: 142: 38.07
+	Hs
		844470 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAB5C_HUMAN (4-196): 2.82e-45: 151: 38.00
+	Mm
		722717 RAB5A_MOUSE (4-198): 8.16e-79: 236: 35.50		RAB5C_MOUSE (4-196): 1.07e-45: 152: 38.00
+	Hs
		844724 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAB5C_HUMAN (4-196): 2.82e-45: 151: 38.00