HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071013 - catalytic step 2 spliceosome and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 378
+	Hs
		161978 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30
+	Hs
		745163 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59
+	Hs
		852206 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00
+	Hs
		745277 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38
+	Hs
		680450 TIA1_HUMAN (2-371): 9.39e-25: 106: 14.81		HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59
+	Hs
		609738 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27
+	Hs
		453192 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20
+	Hs
		745188 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RA1L2_HUMAN (9-108): 1.39e-16: 81.7: 25.96
+	Hs
		1020319 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (6-328): 5.14e-15: 78.6: 12.84
+	Hs
		610108 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27
+	Hs
		745149 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		ROA0_HUMAN (17-115): 5.36e-10: 62: 34.34
+	Hs
		609833 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27
+	Hs
		453706 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20
+	Hs
		453350 CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00		ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20
+	Hs
		516744 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		PABP1_HUMAN (6-328): 5.14e-15: 78.6: 12.84
+	Hs
		1020249 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP4_HUMAN (6-339): 1.18e-16: 83.6: 13.82
+	Hs
		516484 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP1_HUMAN (6-328): 5.14e-15: 78.6: 12.84
+	Mm
		665745 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		PABP1_MOUSE (6-328): 6.56e-15: 78.3: 12.84
+	Hs
		1026045 CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00		ROA0_HUMAN (17-115): 5.36e-10: 62: 34.34