HitPredict

Interactor 1: AIM3 (P38266)
Altered inheritance of mitochondria protein 3
Gene: AIM3

Interactor 2: PIN3 (Q06449)
[PSI+] inducibility protein 3 (LAS seventeen-binding protein 2) (LAS17-binding protein 2)
Gene: PIN3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	19841731
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 947 Sc			1 215
+	Sc
		747560 AIM3_YEAST (1-947): 4.39e-122: 396: 100.00		LSB1_YEAST (1-215): 8.56e-34: 122: 46.28
+	Sc
		747555 AIM3_YEAST (1-947): 4.39e-122: 396: 100.00		LSB3_YEAST (28-109): 2.66e-16: 78.4: 33.33
+	Hs
		554292 MUC1_HUMAN (106-905): 3.55e-33: 140: 11.33		GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54
+	Hs
		302308 SC31A_HUMAN (61-366): 5.83e-14: 78.6: 14.69		STAM1_HUMAN (2-200): 2.11e-32: 124: 14.42
+	Hs
		276974 SC31A_HUMAN (61-366): 5.83e-14: 78.6: 14.69		STAM2_HUMAN (4-200): 6.69e-32: 122: 14.83
+	Hs
		203249 SYNJ1_HUMAN (342-770): 8.89e-16: 84.6: 12.67		SH3G2_HUMAN (10-115): 9.95e-29: 111: 20.76
+	Hs
		203248 SYNJ1_HUMAN (342-770): 8.89e-16: 84.6: 12.67		SH3G1_HUMAN (16-113): 2.65e-27: 108: 28.28
+	Mm
		88459 D3Z656_MOUSE (474-929): 6.43e-10: 65.7: 12.63		SH3G2_MOUSE (10-115): 7.36e-29: 112: 20.76
+	Hs
		1270776 CBP_HUMAN (120-442): 1.08e-10: 68: 18.37		SH3G1_HUMAN (16-113): 2.65e-27: 108: 28.28
+	Hs
		1056870 MDC1_HUMAN (280-884): 4.53e-17: 88.8: 9.49		STAC2_HUMAN (36-132): 8.53e-19: 85.3: 31.96
+	Hs
		1056926 MDC1_HUMAN (280-884): 4.53e-17: 88.8: 9.49		SH3K1_HUMAN (10-117): 3.28e-18: 84.2: 20.35
+	Hs
		203218 SYNJ1_HUMAN (342-770): 8.89e-16: 84.6: 12.67		GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54
+	Hs
		203241 SYNJ1_HUMAN (342-770): 8.89e-16: 84.6: 12.67		SH3K1_HUMAN (10-117): 3.28e-18: 84.2: 20.35
+	Hs
		203246 SYNJ1_HUMAN (342-770): 8.89e-16: 84.6: 12.67		SH3Y1_HUMAN (55-109): 2.76e-16: 78: 43.86
+	Dm
		993211 Q9VUH6_DROME (89-437): 4.17e-11: 69.5: 18.62		GRAP_DROME (59-110): 2.53e-22: 91.8: 42.31
+	Hs
		203228 SYNJ1_HUMAN (342-770): 8.89e-16: 84.6: 12.67		ITSN1_HUMAN (38-128): 8.43e-14: 71.5: 20.83
+	Hs
		924632 TENS2_HUMAN (90-455): 1.55e-11: 70.7: 19.24		GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54
+	Hs
		587810 CBP_HUMAN (120-442): 1.08e-10: 68: 18.37		NCF2_HUMAN (22-122): 5.22e-19: 86.5: 25.74
+	Hs
		924760 PRG4_HUMAN (12-659): 6.88e-11: 68.8: 8.60		GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54
+	Hs
		1186102 MICA3_HUMAN (295-817): 2.56e-10: 66.8: 10.44		CD2AP_HUMAN (59-180): 1.23e-17: 82.6: 21.26