HitPredict

Interactor 1: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Interactor 2: NXF1 (Q9UBU9)
Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)
Gene: NXF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 11073998, 29395067, 11551912, 31375530, 10668806, 16314397, 22334672
Identification Methods pull down, proximity labelling technology, fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1817
Hs

1 619
+ Tt
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024