HitPredict

Interactor 1: YPT7 (P32939)
Ypt/Rab-type GTPase YPT7 (Ypt7p) (Vacuolar morphology protein 4)
Gene: YPT7

Interactor 2: YPT52 (P36018)
GTP-binding protein YPT52
Gene: YPT52

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22157956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005770 - late endosome GO:0005829 - cytosol and 1 others more... GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Sc			1 234
+	Dm
		197035 RAB7_DROME (1-208): 9.54e-87: 256: 58.10		O18332_DROME (4-233): 5.82e-74: 224: 30.87
+	Zm
		77342 B4FAE1_MAIZE (1-207): 2.88e-81: 242: 35.71		B4FAE1_MAIZE (4-234): 1.23e-78: 236: 28.57
+	Hs
		901029 RAB1B_HUMAN (1-208): 1.77e-80: 240: 36.54		RAB5C_HUMAN (3-234): 4.3e-79: 238: 46.55
+	Hs
		900760 RAB1A_HUMAN (1-207): 2.84e-80: 239: 35.89		RAB5C_HUMAN (3-234): 4.3e-79: 238: 46.55
+	Hs
		900968 RAB8B_HUMAN (1-206): 2.85e-80: 239: 35.75		RAB5C_HUMAN (3-234): 4.3e-79: 238: 46.55
+	Hs
		955910 RAB8A_HUMAN (1-206): 1.24e-80: 240: 36.23		RAB1A_HUMAN (4-233): 1.2e-74: 226: 28.26
+	Hs
		981357 RAB1B_HUMAN (1-208): 1.77e-80: 240: 36.54		RAB1A_HUMAN (4-233): 1.2e-74: 226: 28.26
+	Hs
		981254 RAB1A_HUMAN (1-207): 2.84e-80: 239: 35.89		RAB1A_HUMAN (4-233): 1.2e-74: 226: 28.26
+	Hs
		1370778 RAB8B_HUMAN (1-206): 2.85e-80: 239: 35.75		RAB1B_HUMAN (4-233): 1.98e-74: 225: 29.57
+	Mm
		981416 RAB1A_MOUSE (1-207): 2.84e-80: 239: 35.89		RAB1B_MOUSE (4-233): 5.51e-74: 224: 29.57
+	Hs
		955907 RAB8A_HUMAN (1-206): 1.24e-80: 240: 36.23		RB11A_HUMAN (4-233): 1.58e-72: 221: 33.77
+	Hs
		976188 RAB1A_HUMAN (1-207): 2.84e-80: 239: 35.89		RB11A_HUMAN (4-233): 1.58e-72: 221: 33.77
+	Hs
		1356536 RAB1B_HUMAN (1-208): 1.77e-80: 240: 36.54		RAB2B_HUMAN (4-233): 7.96e-72: 219: 28.87
+	Hs
		1155389 RAB1B_HUMAN (1-208): 1.77e-80: 240: 36.54		RB11B_HUMAN (4-233): 4.5e-71: 217: 32.62
+	Hs
		981287 RAB1A_HUMAN (1-207): 2.84e-80: 239: 35.89		RB11B_HUMAN (4-233): 4.5e-71: 217: 32.62
+	Dm
		304134 RAB7_DROME (1-208): 9.54e-87: 256: 58.10		RAB5_DROME (3-233): 1.84e-59: 188: 50.22
+	Sc
		748726 YPT7_YEAST (1-208): 5.57e-81: 241: 100.00		VPS21_YEAST (5-232): 5.99e-57: 181: 48.25
+	Sc
		748728 YPT7_YEAST (1-208): 5.57e-81: 241: 100.00		YPT53_YEAST (2-193): 3.19e-54: 175: 53.13
+	Dm
		197201 RAB7_DROME (1-208): 9.54e-87: 256: 58.10		RAB6_DROME (3-234): 2.85e-38: 134: 34.05
+	Hs
		631633 RAB8A_HUMAN (1-206): 1.24e-80: 240: 36.23		RAB6A_HUMAN (3-224): 2.73e-39: 136: 34.69