Interactor 1: CADH5 (P33151)
Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: CDH5

Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 39232006
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005912 - adherens junction
GO:0010628 - positive regulation of gene expression
and 4 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 784
Hs

1 1824
+ Hs
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Service provided by Combinatics, Japan

Last updated: 11Aug2025