HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34591612, 22990118
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030308 - negative regulation of cell growth GO:0051726 - regulation of cell cycle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 817
+	Hs
		1149890 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		536942 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		585019 RO52_HUMAN (15-390): 2.55e-68: 241: 12.86		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		1252493 TRI39_HUMAN (15-389): 8.42e-67: 238: 13.19		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		1115440 TRI60_HUMAN (10-376): 1.12e-65: 233: 11.53		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		1252534 TRI10_HUMAN (12-342): 2.46e-55: 203: 13.97		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78