HitPredict

Interactor 1: CIC1 (P38779)
Proteasome-interacting protein CIC1 (Core interacting component 1)
Gene: CIC1

Interactor 2: PRP43 (P53131)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 (EC 3.6.4.13) (Helicase JA1)
Gene: PRP43

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 12374754, 16227579
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~Ribosomal_L1
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0030686 - 90S preribosome
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 376
Sc

1 767
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024