HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 1208
+	Hs
		957624 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		DZIP3_HUMAN (1-1208): 0: 1245: 100.00
+	Hs
		982234 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		DZIP3_HUMAN (1-1208): 0: 1245: 100.00
+	Hs
		957127 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		DZIP3_HUMAN (1-1208): 0: 1245: 100.00
+	Hs
		208495 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		PJA2_HUMAN (601-1207): 2.01e-59: 220: 14.47
+	Hs
		208490 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		PJA2_HUMAN (601-1207): 2.01e-59: 220: 14.47
+	Hs
		923579 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		TTC3_HUMAN (703-1207): 3.29e-42: 171: 19.34
+	Hs
		982218 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		ARK2C_HUMAN (1008-1191): 3.16e-29: 122: 17.74
+	Hs
		957109 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		ARK2C_HUMAN (1008-1191): 3.16e-29: 122: 17.74
+	Hs
		982211 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RNF43_HUMAN (1104-1206): 7.88e-24: 110: 26.79
+	Hs
		957101 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		RNF43_HUMAN (1104-1206): 7.88e-24: 110: 26.79
+	Hs
		982363 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RN150_HUMAN (1102-1202): 2.7e-22: 103: 21.36
+	Zm
		77732 B4FC97_MAIZE (1-52): 4.52e-31: 108: 38.46		B6U926_MAIZE (1112-1204): 4.69e-22: 101: 26.60
+	Zm
		83048 B6SZE0_MAIZE (1-52): 1.6e-30: 107: 38.46		B6U926_MAIZE (1112-1204): 4.69e-22: 101: 26.60
+	Hs
		982231 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		GOLI_HUMAN (1107-1194): 1.09e-21: 101: 23.33
+	Hs
		982249 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90
+	Hs
		957124 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		GOLI_HUMAN (1107-1194): 1.09e-21: 101: 23.33
+	Dm
		683053 UBCD1_DROME (1-51): 3.1e-30: 106: 39.22		IRU_DROME (1114-1201): 4.39e-21: 98.7: 26.97
+	At
		762767 UBC9_ARATH (1-52): 8.22e-30: 105: 38.46		RNG1L_ARATH (1112-1203): 4.07e-21: 97.9: 25.81
+	Hs
		982225 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		SYVN1_HUMAN (1108-1192): 8.86e-15: 80.9: 32.58
+	Hs
		957118 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		SYVN1_HUMAN (1108-1192): 8.86e-15: 80.9: 32.58