HitPredict

Interactor 1: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Interactor 2: CXCR3 (P49682)
C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)
Gene: CXCR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 857 Hs			1 368
+	Hs
		755552 TTK_HUMAN (1-857): 0: 778: 100.00		GPR17_HUMAN (9-362): 7.18e-80: 250: 27.82
+	Hs
		755525 TTK_HUMAN (1-857): 0: 778: 100.00		APJ_HUMAN (33-367): 8.9e-68: 219: 27.76
+	Hs
		755541 TTK_HUMAN (1-857): 0: 778: 100.00		CXCR4_HUMAN (22-333): 1.53e-67: 218: 36.42
+	Hs
		1101721 M3K4_HUMAN (530-795): 2.2e-22: 105: 27.47		GPR17_HUMAN (9-362): 7.18e-80: 250: 27.82
+	Hs
		886158 M3K4_HUMAN (530-795): 2.2e-22: 105: 27.47		CXCR3_HUMAN (1-368): 6.85e-78: 245: 100.00