Interactor 1: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Interactor 2: MGN (P61326)
Protein mago nashi homolog
Gene: MAGOH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 14730019, 23084401, 22961380, 37071682, 18066079, 19478851, 16170325, 19410547, 16209946, 16601204
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Mago_nashi, Helicase_C~Mago_nashi
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 411
Hs

1 146
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ At
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024