HitPredict

Interactor 1: LIN36 (P34427)
Protein lin-36 (Abnormal cell lineage protein 36)
Gene: lin-36

Interactor 2: SYIC (Q21926)
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
Gene: iars-1

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	12679813, 10615043, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 962 Ce			1 1141
+	Hs
		834480 HUWE1_HUMAN (501-913): 2.13e-34: 145: 18.59		SYIC_HUMAN (4-1071): 0: 1094: 58.24
+	Hs
		687833 HUWE1_HUMAN (501-913): 2.13e-34: 145: 18.59		SYVC_HUMAN (2-963): 0: 852: 19.20
+	Hs
		1210589 HUWE1_HUMAN (501-913): 2.13e-34: 145: 18.59		SYVM_HUMAN (2-972): 0: 772: 18.39
+	Hs
		1280564 HUWE1_HUMAN (501-913): 2.13e-34: 145: 18.59		SYLC_HUMAN (1-985): 0: 686: 15.39
+	Hs
		161519 KMT2D_HUMAN (462-931): 1.98e-10: 67.5: 10.19		SYLC_HUMAN (1-985): 0: 686: 15.39