Interactor 1: COFA1 (P39059)
Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)]
Gene: COL15A1

Interactor 2: COFA1 (P39059)
Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)]
Gene: COL15A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.730

The method score is based on:

Property Details
Experiments 20932905
Identification Methods cosedimentation in solution, protein cross-linking with a bifunctional reagent, molecular sieving, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Collagen~Collagen, Collagen_trimer~Collagen_trimer, Endostatin~Endostatin
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005582 - collagen type XV trimer
GO:0005604 - basement membrane
GO:0005615 - extracellular space
and 9 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1388
Hs

1 1388
+ Ce
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024