HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: DNJC5 (Q9H3Z4)
DnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP)
Gene: DNAJC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29167402, 19098309
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 198
+	Hs
		761914 HSP74_HUMAN (1-840): 0: 996: 100.00		DNJ5B_HUMAN (1-195): 4.02e-70: 213: 68.21
+	Hs
		298891 HSP74_HUMAN (1-840): 0: 996: 100.00		DNJB5_HUMAN (13-108): 5.34e-40: 141: 38.10
+	Hs
		679307 HSP74_HUMAN (1-840): 0: 996: 100.00		DNJB2_HUMAN (15-117): 1.4e-39: 139: 35.25
+	Hs
		761913 HSP74_HUMAN (1-840): 0: 996: 100.00		DNJB4_HUMAN (13-85): 1.08e-37: 134: 52.06
+	Hs
		761785 HSP74_HUMAN (1-840): 0: 996: 100.00		DNJB3_HUMAN (15-112): 3.39e-39: 132: 38.18
+	Hs
		343900 HS74L_HUMAN (1-840): 0: 961: 63.21		DNJB2_HUMAN (15-117): 1.4e-39: 139: 35.25
+	Hs
		298943 HS105_HUMAN (1-840): 0: 939: 62.95		DNJB5_HUMAN (13-108): 5.34e-40: 141: 38.10
+	Hs
		1202471 HS105_HUMAN (1-840): 0: 939: 62.95		Q59E89_HUMAN (13-85): 1.5e-37: 134: 52.06
+	Hs
		1365257 HS105_HUMAN (1-840): 0: 939: 62.95		DNJB4_HUMAN (13-85): 1.08e-37: 134: 52.06
+	Hs
		274687 HS105_HUMAN (1-840): 0: 939: 62.95		DNJB6_HUMAN (17-79): 1.09e-20: 89.4: 60.94
+	Dm
		1172265 Q9VUC1_DROME (1-840): 0: 821: 42.10		DNAJ1_DROME (13-164): 2.72e-40: 141: 27.22
+	Ce
		482117 HSP1_CAEEL (2-603): 0: 811: 31.48		Q20774_CAEEL (13-109): 2.5e-40: 141: 40.19
+	Hs
		537696 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		DNJA3_HUMAN (6-117): 1.21e-42: 150: 31.93
+	Hs
		298882 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		DNJB5_HUMAN (13-108): 5.34e-40: 141: 38.10
+	Hs
		516181 HS71B_HUMAN (564-686): 7.69e-19: 93.5: 21.77		DNJB2_HUMAN (15-117): 1.4e-39: 139: 35.25
+	Hs
		536530 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		DNJB2_HUMAN (15-117): 1.4e-39: 139: 35.25
+	Hs
		516217 HS71B_HUMAN (564-686): 7.69e-19: 93.5: 21.77		DNJB4_HUMAN (13-85): 1.08e-37: 134: 52.06
+	Hs
		537603 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		DNJB3_HUMAN (15-112): 3.39e-39: 132: 38.18
+	Hs
		274447 HS71A_HUMAN (564-686): 7.69e-19: 93.5: 21.77		DNJB6_HUMAN (17-79): 1.09e-20: 89.4: 60.94
+	Hs
		274453 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		DNJB6_HUMAN (17-79): 1.09e-20: 89.4: 60.94