HitPredict

Interactor 1: PROF2 (P35080)
Profilin-2 (Profilin II)
Gene: PFN2

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9843499
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005856 - cytoskeleton GO:0098794 - postsynapse GO:0098885 - modification of postsynaptic actin cytoskeleton
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 559
+	Mm
		1341703 PROF2_MOUSE (1-140): 3.32e-76: 224: 99.29		WASF1_MOUSE (1-559): 6.22e-71: 239: 98.39
+	Hs
		459703 PROF1_HUMAN (1-140): 4.27e-74: 219: 61.43		WASF1_HUMAN (1-559): 2.43e-72: 243: 100.00
+	Hs
		459828 PROF1_HUMAN (1-140): 4.27e-74: 219: 61.43		WASF2_HUMAN (1-541): 1.82e-39: 152: 42.33
+	Hs
		176241 PROF1_HUMAN (1-140): 4.27e-74: 219: 61.43		SYNJ2_HUMAN (46-507): 1.46e-30: 129: 14.71
+	Hs
		215894 PROF1_HUMAN (1-140): 4.27e-74: 219: 61.43		SYNJ1_HUMAN (284-555): 3.16e-12: 71.7: 13.43
+	Mm
		1440872 PROF2_MOUSE (1-140): 3.32e-76: 224: 99.29		PCLO_MOUSE (75-539): 5.23e-09: 61.7: 13.92
+	Mm
		986967 PROF1_MOUSE (1-140): 1.25e-73: 217: 62.86		PCLO_MOUSE (75-539): 5.23e-09: 61.7: 13.92