HitPredict

Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: RAB2A (P61019)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 212
+	Dm
		197045 PHB1_DROME (1-271): 7.42e-93: 276: 75.28		O18332_DROME (3-212): 1.03e-91: 268: 43.81
+	Hs
		766402 PHB1_HUMAN (1-272): 1.19e-95: 283: 100.00		RB11A_HUMAN (3-212): 1.39e-84: 251: 46.67
+	Hs
		956457 PHB2_HUMAN (6-267): 3.63e-88: 266: 50.57		RAB2A_HUMAN (1-212): 3.69e-89: 262: 100.00
+	Hs
		976511 PHB2_HUMAN (6-267): 3.63e-88: 266: 50.57		RB11A_HUMAN (3-212): 1.39e-84: 251: 46.67
+	Hs
		630703 PHB1_HUMAN (1-272): 1.19e-95: 283: 100.00		RAB4A_HUMAN (3-188): 6.94e-72: 219: 57.53
+	Mm
		994451 PHB1_MOUSE (1-272): 9.34e-96: 284: 99.63		RAB4B_MOUSE (3-188): 3.9e-71: 217: 55.91
+	Hs
		630949 PHB2_HUMAN (6-267): 3.63e-88: 266: 50.57		RAB4A_HUMAN (3-188): 6.94e-72: 219: 57.53
+	Dm
		197114 Q9VWL0_DROME (4-268): 5.33e-68: 216: 20.90		O18332_DROME (3-212): 1.03e-91: 268: 43.81
+	Mm
		204295 PHB2_MOUSE (6-267): 3.63e-88: 266: 50.57		RAB4B_MOUSE (3-188): 3.9e-71: 217: 55.91
+	Hs
		690220 STOM_HUMAN (1-265): 2.35e-70: 220: 17.91		RAB2A_HUMAN (1-212): 3.69e-89: 262: 100.00
+	Dm
		197185 Q9VWL0_DROME (4-268): 5.33e-68: 216: 20.90		RAB2_DROME (1-212): 2.8e-88: 260: 88.73
+	Hs
		76684 B4E2V5_HUMAN (34-265): 3.72e-57: 184: 19.57		RAB2A_HUMAN (1-212): 3.69e-89: 262: 100.00