Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.996

The method score is based on:

Property Details
Experiments 29401731, 11739384, 12697815, 17922844, 18187417, 15935760, 10205047, 10449727, 25500545, 25661653, 26735018, 26751167, 27517496, 28514442, 28775317, 17353931, 29121446, 30267325, 10587522, 8674032 and 35 others

more...

Identification Methods affinity chromatography technology, pull down, x-ray crystallography, two hybrid, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Skp1_POZ~VHL, Skp1_POZ~VHL_C
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 213
Hs

1 112
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024