Interactor 1: MED3 (P40356)
Mediator of RNA polymerase II transcription subunit 3 (Hyper-recombination suppressor protein 1) (Mediator complex subunit 3) (Poly-glutamine domain protein 1)
Gene: PGD1

Interactor 2: MED2 (Q12124)
Mediator of RNA polymerase II transcription subunit 2 (Mediator complex subunit 2)
Gene: MED2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.55 0.716

The method score is based on:

Property Details
Experiments 11805826, 9420330, 10949041, 16554755, 16230344, 37968396, 21498544, 16429126, 24882805
Identification Methods tandem affinity purification, biochemical, affinity chromatography technology, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 5 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024