Interactor 1: ACTN2 (P35609)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2
Interactor 2: KCNN2 (Q9H2S1)
Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)
Gene: KCNN2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.713 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19815520 |
| Identification Methods | pull down, two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CaMBD~EF-hand_7 |
| Common GO terms | GO:0019904 - protein domain specific binding GO:0030018 - Z disc GO:0043197 - dendritic spine |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
