HitPredict

Interactor 1: ULP2 (P40537)
Ubiquitin-like-specific protease 2 (EC 3.4.22.-)
Gene: ULP2

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.924

Property	Details
Experiments	23122649, 20516210, 25833950, 27631802, 29903909
Identification Methods	unspecified method, enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Peptidase_C48~Rad60-SLD
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1034 Sc			1 101
+	Hs
		902760 SENP2_HUMAN (230-665): 1.24e-107: 349: 17.81		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		879156 SENP2_HUMAN (230-665): 1.24e-107: 349: 17.81		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Hs
		928203 SENP2_HUMAN (230-665): 1.24e-107: 349: 17.81		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Sp
		140818 ULP2_SCHPO (268-698): 7.68e-100: 329: 22.20		PMT3_SCHPO (4-101): 2.02e-37: 123: 53.00
+	Hs
		902714 SENP5_HUMAN (211-666): 5.51e-99: 331: 16.42		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		879147 SENP5_HUMAN (211-666): 5.51e-99: 331: 16.42		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Xl
		1151579 Q804S7_XENLA (256-665): 4.72e-97: 321: 17.42		SMO2B_XENLA (9-99): 3.47e-36: 119: 42.39
+	Xl
		1125459 Q804S7_XENLA (256-665): 4.72e-97: 321: 17.42		SMO1B_XENLA (1-98): 6.32e-35: 116: 45.46
+	Hs
		902778 SENP1_HUMAN (306-665): 2.6e-93: 312: 18.65		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		879158 SENP1_HUMAN (306-665): 2.6e-93: 312: 18.65		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Hs
		928213 SENP1_HUMAN (306-665): 2.6e-93: 312: 18.65		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Xl
		80969 B7TYL2_XENLA (232-695): 1.52e-85: 297: 15.87		SMO2B_XENLA (9-99): 3.47e-36: 119: 42.39
+	Hs
		902739 SENP7_HUMAN (245-694): 7.63e-83: 292: 15.51		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Sp
		140841 ULP1_SCHPO (229-665): 5.01e-78: 268: 17.47		PMT3_SCHPO (4-101): 2.02e-37: 123: 53.00
+	Xl
		78631 B6RQN8_XENLA (270-666): 9.09e-75: 263: 14.01		SMO2B_XENLA (9-99): 3.47e-36: 119: 42.39
+	Ce
		879054 SENP_CAEEL (268-665): 1.79e-77: 270: 17.85		SUMO_CAEEL (12-98): 3.17e-32: 109: 39.77
+	Xl
		1140103 Q5XG28_XENLA (297-664): 5.35e-76: 259: 16.93		SMO2B_XENLA (9-99): 3.47e-36: 119: 42.39
+	Hs
		902753 SENP3_HUMAN (295-664): 2.91e-73: 255: 18.49		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Dm
		332584 Q9VWK5_DROME (343-666): 1.66e-59: 225: 17.91		O97102_DROME (13-99): 2.66e-35: 117: 43.18
+	Sc
		972033 ULP1_YEAST (225-664): 3.96e-56: 207: 17.17		SMT3_YEAST (1-101): 1.79e-40: 130: 100.00