HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	12620224, 17049045, 34056863, 37968396, 14690608, 21179020
Identification Methods	pull down, affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Sc			1 136
+	Sp
		489138 YK82_SCHPO (6-672): 2.45e-111: 354: 24.89		H31_SCHPO (1-136): 1.45e-58: 179: 92.65
+	Sc
		963751 BDF2_YEAST (84-615): 7.77e-82: 273: 38.04		H3_YEAST (1-136): 1.85e-55: 171: 100.00
+	Dm
		381725 Q9VC96_DROME (114-684): 4.57e-71: 254: 16.75		H3_DROME (1-136): 2.01e-59: 181: 88.97
+	Dm
		381706 Q4V5A7_DROME (123-684): 1.01e-67: 236: 13.88		H3_DROME (1-136): 2.01e-59: 181: 88.97
+	Hs
		639710 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		639713 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		998836 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		1017230 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		639746 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Hs
		1162054 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Hs
		1258957 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		H32_HUMAN (1-136): 2.01e-59: 181: 88.97
+	Hs
		1017013 TAF1L_HUMAN (115-578): 1.17e-53: 202: 14.62		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Sc
		963658 RSC4_YEAST (105-686): 7.61e-56: 203: 15.22		H3_YEAST (1-136): 1.85e-55: 171: 100.00
+	Hs
		639684 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		CENPA_HUMAN (9-133): 1.33e-44: 144: 47.73
+	Hs
		883697 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		CENPA_HUMAN (9-133): 1.33e-44: 144: 47.73
+	Hs
		998491 PB1_HUMAN (91-664): 2.89e-39: 158: 12.56		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		1016988 PB1_HUMAN (91-664): 2.89e-39: 158: 12.56		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		1161923 PB1_HUMAN (91-664): 2.89e-39: 158: 12.56		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Sc
		779322 RSC4_YEAST (105-686): 7.61e-56: 203: 15.22		CENPA_YEAST (24-134): 1.34e-40: 136: 53.04
+	Hs
		883596 PB1_HUMAN (91-664): 2.89e-39: 158: 12.56		CENPA_HUMAN (9-133): 1.33e-44: 144: 47.73