HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: ESA1 (Q08649)
Histone acetyltransferase ESA1 (EC 2.3.1.48) (Protein 2-hydroxyisobutyryltransferase ESA1) (EC 2.3.1.-) (Protein acetyltransferase ESA1) (EC 2.3.1.-) (Protein crotonyltransferase ESA1) (EC 2.3.1.-)
Gene: ESA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	21179020, 15353583
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Sc			1 445
+	Sc
		1059307 BDF2_YEAST (84-615): 7.77e-82: 273: 38.04		ESA1_YEAST (1-445): 0: 608: 100.00
+	Sc
		757756 BDF1_YEAST (1-671): 1.97e-150: 454: 100.00		SAS3_YEAST (91-439): 1.17e-131: 401: 34.53
+	Hs
		331961 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		332051 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		331940 BRD1_HUMAN (40-340): 4.53e-37: 151: 13.78		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		332061 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		342272 BRD1_HUMAN (40-340): 4.53e-37: 151: 13.78		KAT6B_HUMAN (93-439): 6.56e-158: 493: 41.43
+	Hs
		1287967 PB1_HUMAN (91-664): 2.89e-39: 158: 12.56		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		1361561 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		KAT6B_HUMAN (93-439): 6.56e-158: 493: 41.43
+	Hs
		342279 BRD1_HUMAN (40-340): 4.53e-37: 151: 13.78		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		1368445 CBP_HUMAN (249-418): 1.17e-36: 150: 25.73		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		331963 BRD2_HUMAN (297-569): 2.1e-27: 120: 17.83		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		332004 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		259247 BRD4_HUMAN (267-427): 2.87e-26: 117: 26.71		KAT7_HUMAN (50-434): 1.11e-178: 514: 39.55
+	Hs
		1368672 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Sc
		757772 RSC4_YEAST (105-686): 7.61e-56: 203: 15.22		SAS3_YEAST (91-439): 1.17e-131: 401: 34.53
+	Hs
		342282 BRD1_HUMAN (40-340): 4.53e-37: 151: 13.78		KAT5_HUMAN (17-165): 3.98e-19: 91.7: 27.27
+	Hs
		1368451 CBP_HUMAN (249-418): 1.17e-36: 150: 25.73		KAT5_HUMAN (17-165): 3.98e-19: 91.7: 27.27
+	Hs
		1371329 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		KAT5_HUMAN (17-165): 3.98e-19: 91.7: 27.27
+	Hs
		1141341 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		MO4L1_HUMAN (20-180): 9.01e-13: 71.2: 11.50