HitPredict

Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16049137
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005768 - endosome GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1356 Hs			1 870
+	Hs
		593311 PGFRA_HUMAN (11-458): 2.1e-52: 203: 22.10		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		609968 VGFR1_HUMAN (1-123): 7.12e-20: 98.9: 14.18		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		650091 FGFR3_HUMAN (1-120): 6.18e-18: 92: 16.90		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		541398 FGFR1_HUMAN (1-169): 9.76e-17: 88.1: 13.54		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		648463 FGFR4_HUMAN (1-120): 3.81e-16: 86.2: 15.71		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		641139 FGFR2_HUMAN (1-124): 1.47e-15: 84.3: 15.07		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		650492 FGFR3_HUMAN (1-120): 6.18e-18: 92: 16.90		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		541760 FGFR1_HUMAN (1-169): 9.76e-17: 88.1: 13.54		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		648743 FGFR4_HUMAN (1-120): 3.81e-16: 86.2: 15.71		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		641285 FGFR2_HUMAN (1-124): 1.47e-15: 84.3: 15.07		DYN3_HUMAN (1-870): 0: 994: 78.41