HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 870
+	Hs
		411593 NTRK1_HUMAN (158-756): 6.61e-146: 449: 27.02		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		411781 NTRK1_HUMAN (158-756): 6.61e-146: 449: 27.02		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		135447 NTRK1_HUMAN (158-756): 6.61e-146: 449: 27.02		DNM1L_HUMAN (6-743): 0: 787: 39.13
+	Hs
		778039 VGFR2_HUMAN (5-342): 3.96e-17: 88.6: 16.32		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		609968 VGFR1_HUMAN (40-357): 4.88e-13: 75.2: 13.25		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		541398 FGFR1_HUMAN (1-114): 5.62e-13: 74.7: 18.32		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		648463 FGFR4_HUMAN (1-130): 1.38e-11: 70.1: 17.93		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		641139 FGFR2_HUMAN (1-137): 5.98e-11: 68.2: 18.18		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		541760 FGFR1_HUMAN (1-114): 5.62e-13: 74.7: 18.32		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		650492 FGFR3_HUMAN (1-153): 9.78e-13: 74: 15.88		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		648743 FGFR4_HUMAN (1-130): 1.38e-11: 70.1: 17.93		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		641285 FGFR2_HUMAN (1-137): 5.98e-11: 68.2: 18.18		DYN3_HUMAN (1-870): 0: 994: 78.41