HitPredict

Interactor 1: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	24632723, 11805080, 16678999
Identification Methods	affinity chromatography technology, pull down, two hybrid, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031295 - T cell costimulation GO:0071375 - cellular response to peptide hormone stimulus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 178
+	Mm
		782843 CSK_MOUSE (1-450): 0: 543: 99.11		CAV1_MOUSE (1-178): 4.63e-108: 308: 94.94
+	Hs
		337434 ABL1_HUMAN (5-447): 1.78e-164: 494: 37.83		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		522924 SRC_HUMAN (12-442): 8.48e-171: 491: 39.33		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		433327 YES_HUMAN (12-442): 5.99e-170: 490: 37.30		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		789059 ABL2_HUMAN (4-443): 1.63e-160: 485: 39.33		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		433711 LYN_HUMAN (4-445): 3.75e-160: 463: 37.12		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Mm
		403424 SRC_MOUSE (12-442): 1.93e-169: 488: 39.55		CAV3_MOUSE (35-177): 1.81e-76: 227: 65.73
+	Hs
		522865 SRC_HUMAN (12-442): 8.48e-171: 491: 39.33		CAV2_HUMAN (53-177): 5.1e-59: 183: 40.80