Interactor 1: M3K8 (P41279)
Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2)
Gene: MAP3K8
Interactor 2: PIN1 (Q13526)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1)
Gene: PIN1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 0.60 | 0.594 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24265246 |
| Identification Methods | anti tag coimmunoprecipitation, two hybrid, pull down, anti bait coimmunoprecipitation, protein kinase assay |
| Interaction Type | physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0007049 - cell cycle |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
