Interactor 1: GRIA1 (P42261)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1)
Gene: GRIA1

Interactor 2: CCG2 (Q9Y698)
Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2)
Gene: CACNG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 11140673, 16793768
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Lig_chan~PMP22_Claudin, Lig_chan-Glu_bd~PMP22_Claudin
Common GO terms GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0030666 - endocytic vesicle membrane
GO:0032281 - AMPA glutamate receptor complex
GO:0098839 - postsynaptic density membrane
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 906
Hs

1 323
+ Rn
+ Mm
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Rn
+ Rn
+ Mm
+ Rn
+ Mm
+ Ce

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Last updated: 15 Jul 2024