HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: ERBIN (Q96RT1)
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
Gene: ERBIN

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	26186194, 27880917, 28514442, 28330616, 30344098, 33961781, unassigned3799, 24366813
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~Metallophos, Metallophos~PDZ, LRR_8~STPPase_N, PDZ~STPPase_N
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016607 - nuclear speck GO:0098978 - glutamatergic synapse
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1412
+	Hs
		967931 PP1A_HUMAN (1-323): 0: 579: 90.66		ERBIN_HUMAN (8-1412): 0: 901: 100.00
+	Hs
		967924 PP1A_HUMAN (1-323): 0: 579: 90.66		LRRC7_HUMAN (8-1411): 0: 652: 36.89
+	Hs
		786937 PP1G_HUMAN (1-323): 0: 603: 100.00		SHOC2_HUMAN (188-585): 1.18e-49: 188: 20.49
+	Dm
		559065 PP12_DROME (5-303): 0: 551: 93.31		SUR8_DROME (158-584): 4.58e-60: 221: 21.02
+	Hs
		968040 PP1A_HUMAN (1-323): 0: 579: 90.66		SHOC2_HUMAN (188-585): 1.18e-49: 188: 20.49
+	Hs
		786599 PP1G_HUMAN (1-323): 0: 603: 100.00		SCRIB_HUMAN (1-218): 1.94e-39: 163: 29.36
+	Hs
		968489 PP1B_HUMAN (1-322): 0: 560: 86.89		SHOC2_HUMAN (188-585): 1.18e-49: 188: 20.49
+	Hs
		967723 PP1A_HUMAN (1-323): 0: 579: 90.66		SCRIB_HUMAN (1-218): 1.94e-39: 163: 29.36
+	Hs
		968296 PP1B_HUMAN (1-322): 0: 560: 86.89		SCRIB_HUMAN (1-218): 1.94e-39: 163: 29.36
+	Hs
		786579 PP1G_HUMAN (1-323): 0: 603: 100.00		FLII_HUMAN (94-449): 1.2e-20: 101: 28.27
+	Hs
		967696 PP1A_HUMAN (1-323): 0: 579: 90.66		FLII_HUMAN (94-449): 1.2e-20: 101: 28.27
+	Hs
		786814 PP1G_HUMAN (1-323): 0: 603: 100.00		LRRC1_HUMAN (380-819): 2.09e-12: 73.3: 10.91
+	Hs
		968279 PP1B_HUMAN (1-322): 0: 560: 86.89		FLII_HUMAN (94-449): 1.2e-20: 101: 28.27
+	Mm
		968131 PP1A_MOUSE (1-323): 0: 579: 90.36		LRRC1_MOUSE (380-894): 1.79e-12: 73.7: 10.36
+	Hs
		967947 PP1A_HUMAN (1-323): 0: 579: 90.66		LRRC1_HUMAN (380-819): 2.09e-12: 73.3: 10.91
+	Dm
		559041 PP12_DROME (5-303): 0: 551: 93.31		SCRIB_DROME (613-1411): 3.94e-15: 83.4: 12.49
+	Hs
		968429 PP1B_HUMAN (1-322): 0: 560: 86.89		LRRC1_HUMAN (380-819): 2.09e-12: 73.3: 10.91