Interactor 1: MTREX (P42285)
Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase)
Gene: MTREX

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~DSHCT, DSHCT~Helicase_C, Helicase_C~Helicase_C, DEAD~rRNA_proc-arch, Helicase_C~rRNA_proc-arch
Common GO terms GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1042
Hs

1 783
+ Sc
+ Sc
+ Sp
+ Sp
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024