HitPredict

Interactor 1: TEC (P42680)
Tyrosine-protein kinase Tec (EC 2.7.10.2)
Gene: TEC

Interactor 2: ANR54 (Q6NXT1)
Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein)
Gene: ANKRD54

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	32707033, 36736316
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 631 Hs			1 300
+	Mm
		976833 ITK_MOUSE (1-625): 0: 684: 57.12		ANR54_MOUSE (1-300): 4.51e-70: 220: 92.00
+	Hs
		986383 BTK_HUMAN (5-627): 0: 629: 52.50		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		846484 BLK_HUMAN (150-628): 1.68e-169: 494: 38.43		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		523028 SRC_HUMAN (127-627): 2.29e-166: 487: 35.24		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		433389 YES_HUMAN (111-627): 3.51e-163: 479: 34.08		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		411697 LCK_HUMAN (151-627): 2.3e-158: 466: 35.34		ANK3_HUMAN (83-297): 6.75e-61: 211: 20.31
+	Hs
		411885 LCK_HUMAN (151-627): 2.3e-158: 466: 35.34		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Mm
		639458 LYN_MOUSE (144-627): 2.15e-152: 451: 34.21		ANR54_MOUSE (1-300): 4.51e-70: 220: 92.00
+	Hs
		433832 LYN_HUMAN (145-627): 8.36e-153: 452: 34.68		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		433730 LYN_HUMAN (145-627): 8.36e-153: 452: 34.68		ANK3_HUMAN (83-297): 6.75e-61: 211: 20.31
+	Hs
		337406 ABL1_HUMAN (143-624): 2.71e-169: 514: 37.30		DAPK1_HUMAN (103-298): 1.54e-38: 146: 19.19
+	Hs
		433701 LYN_HUMAN (145-627): 8.36e-153: 452: 34.68		ANK2_HUMAN (82-297): 7.44e-60: 208: 19.62
+	Hs
		434071 LYN_HUMAN (145-627): 8.36e-153: 452: 34.68		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Dm
		337696 SRC64_DROME (144-631): 3.95e-167: 490: 34.95		TNKS_DROME (24-295): 3.24e-30: 121: 15.83
+	Hs
		434072 LYN_HUMAN (145-627): 8.36e-153: 452: 34.68		ANR50_HUMAN (124-297): 4.84e-39: 148: 21.17