Protein: PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B (Ankyrin repeat domain-containing protein 4) (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein) (hTIMAP)

Gene: PP16B, PPP1R16B
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q96T49

Gene Ontology (top 5):
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0004857 - enzyme inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

669144

ARBK1
Beta-adrenergic receptor kinase 1

2

3

High-throughput

0.811

High

1403316

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

0

High-throughput

0.742

High

968420

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

4

20

High-throughput

0.710

High

1403314

HPLN2
Hyaluronan and proteoglycan link protein 2

2

2

High-throughput

0.700

High

967936

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

4

20

High-throughput

0.698

High

1349286

ZN564
Zinc finger protein 564

4

2

High-throughput

0.698

High

249189

DSCAM
Cell adhesion molecule DSCAM

1

8

High-throughput

0.698

High

943613

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

3

High-throughput

0.698

High

50376

PXDNL
Probable oxidoreductase PXDNL

1

1

High-throughput

0.691

High

1403319

IKZF3
Zinc finger protein Aiolos

3

1

High-throughput

0.680

High

289667

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

2

High-throughput

0.665

High

1148873

PP1R7
Protein phosphatase 1 regulatory subunit 7

3

5

High-throughput

0.662

High

600362

ZNF24
Zinc finger protein 24

2

2

High-throughput

0.628

High

786804

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

20

High-throughput

0.628

High

1273084

ZN627
Zinc finger protein 627

2

3

High-throughput

0.628

High

210098

CRX
Cone-rod homeobox protein

2

1

High-throughput

0.628

High

1148543

SF3B4
Splicing factor 3B subunit 4

2

2

High-throughput

0.628

High

1312484

PHC2
Polyhomeotic-like protein 2

2

5

High-throughput

0.628

High

1198508

CEP55
Centrosomal protein of 55 kDa

2

0

High-throughput

0.623

High

1063558

GOGA2
Golgin subfamily A member 2

3

9

High-throughput

0.621

High

1403317

KLH13
Kelch-like protein 13

1

1

High-throughput

0.618

High

787444

TGFR1
TGF-beta receptor type-1

1

4

Small-scale

0.618

High

1004174

CXAR
Coxsackievirus and adenovirus receptor

1

6

High-throughput

0.618

High

334457

SYFM
Phenylalanine--tRNA ligase, mitochondrial

2

2

High-throughput

0.606

High

570569

GFAP
Glial fibrillary acidic protein

2

12

High-throughput

0.606

High

829132

RFC5
Replication factor C subunit 5

2

3

High-throughput

0.606

High

1193126

PKHN1
Pleckstrin homology domain-containing family N member 1

2

1

High-throughput

0.606

High

1363730

SHC3
SHC-transforming protein 3

2

10

High-throughput

0.606

High

1403312

SCNM1
Sodium channel modifier 1

2

1

High-throughput

0.606

High

961093

MGN
Protein mago nashi homolog

2

0

High-throughput

0.580

High

1289423

FA83A
Protein FAM83A

2

0

High-throughput

0.580

High

1309146

MISP
Mitotic interactor and substrate of PLK1

2

0

High-throughput

0.580

High

1328056

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.580

High

1392124

CDA7L
Cell division cycle-associated 7-like protein

1

1

High-throughput

0.573

High

159815

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

11

High-throughput

0.560

High

1061837

TLE5
TLE family member 5

1

3

High-throughput

0.560

High

1290553

ZN410
Zinc finger protein 410

1

3

High-throughput

0.560

High

1372044

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.560

High

1403318

TFP11
Tuftelin-interacting protein 11

1

2

High-throughput

0.560

High

907544

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.554

High

1162772

GLO2
Hydroxyacylglutathione hydrolase, mitochondrial

1

2

High-throughput

0.554

High

1295707

HORN
Hornerin

1

5

High-throughput

0.554

High

1371413

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

11

High-throughput

0.553

High

1403308

THIOM
Thioredoxin, mitochondrial

2

6

High-throughput

0.553

High

283537

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.549

High

590481

GATA1
Erythroid transcription factor

1

0

High-throughput

0.536

High

161676

TRDMT
tRNA

1

1

High-throughput

0.536

High

1207423

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.536

High

973543

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.530

High

1218951

TASO2
Protein TASOR 2

1

15

High-throughput

0.523

High

1271395

KCTD9
BTB/POZ domain-containing protein KCTD9

1

11

High-throughput

0.523

High

116875

I6L9F6
NEFL protein

1

13

High-throughput

0.515

High

833346

PERI
Peripherin

1

12

High-throughput

0.515

High

843896

HD
Huntingtin

1

2

High-throughput

0.515

High

91777

MCRI1
Mapk-regulated corepressor-interacting protein 1

1

0

High-throughput

0.513

High

1403310

NTM1A
N-terminal Xaa-Pro-Lys N-methyltransferase 1

1

0

High-throughput

0.513

High

1403313

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.513

High

1403315

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

0

High-throughput

0.513

High

216792

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

451249

NFL
Neurofilament light polypeptide

1

13

High-throughput

0.481

High

788998

TGFR2
TGF-beta receptor type-2

1

4

Small-scale

0.479

High

532887

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.445

High

1227318

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.437

High

863425

GLYG
Glycogenin-1

1

0

High-throughput

0.426

High

1196965

FWCH1
FLYWCH-type zinc finger-containing protein 1

2

0

High-throughput

0.316

High

1403309

TACO1
Translational activator of cytochrome c oxidase 1

2

0

High-throughput

0.316

High

1340326

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.299

High

1403311

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025