HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	23472066, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 255
+	Hs
		909455 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910162 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		883468 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910023 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		60315 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		257595 ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909789 ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909924 ANR27_HUMAN (2-85): 2.82e-15: 73.8: 21.59		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909999 TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910104 RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		56841 TANC2_MOUSE (1-99): 3.54e-10: 59.3: 21.57		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		910048 TANC2_HUMAN (1-99): 3.54e-10: 59.3: 21.57		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00