Protein: CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX (ATP-dependent unfoldase ClpX)

Gene: CLPX
Organism: Escherichia coli K-12
Interactions: 37
UniProt ID: P0A6H1

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004176 - ATP-dependent peptidase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

490285

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

4

14

Small-scale

0.915

High

490228

CLPP
ATP-dependent Clp protease proteolytic subunit

3

6

Small-scale

0.857

High

490304

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

1

14

High-throughput

0.625

High

490316

CLPB
Chaperone protein ClpB

1

11

High-throughput

0.625

High

490288

DNAK
Chaperone protein DnaK

2

8

High-throughput

0.612

High

490286

HSCB
Co-chaperone protein HscB

2

2

High-throughput

0.588

High

490294

METK
S-adenosylmethionine synthase

2

1

High-throughput

0.588

High

490300

MREB
Cell shape-determining protein MreB

2

13

High-throughput

0.588

High

490301

PSTB
Phosphate import ATP-binding protein PstB

2

1

High-throughput

0.588

High

490307

AHPC
Alkyl hydroperoxide reductase C

2

3

High-throughput

0.588

High

490299

FTSZ
Cell division protein FtsZ

1

1

Small-scale

0.561

High

490302

HYPB
Hydrogenase maturation factor HypB

1

1

High-throughput

0.536

High

490303

PUR8
Adenylosuccinate lyase

1

3

High-throughput

0.536

High

490306

YIBL
Uncharacterized protein YibL

1

1

High-throughput

0.536

High

490308

RHO
Transcription termination factor Rho

1

3

High-throughput

0.536

High

490311

NADE
NH(3)-dependent NAD(+) synthetase

1

1

High-throughput

0.536

High

490312

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.536

High

490295

RAPZ
RNase adapter protein RapZ

1

0

High-throughput

0.513

High

490296

YBED
UPF0250 protein YbeD

1

0

High-throughput

0.513

High

490298

CHEW
Chemotaxis protein CheW

1

0

High-throughput

0.513

High

490313

INTD
Prophage integrase IntD

1

0

High-throughput

0.513

High

367514

PABA
Aminodeoxychorismate synthase component 2

1

1

High-throughput

0.489

High

490305

SDHA
Succinate dehydrogenase flavoprotein subunit

1

2

High-throughput

0.489

High

480521

GRPE
Protein GrpE

1

1

High-throughput

0.484

High

490291

RL7
Large ribosomal subunit protein bL12

1

3

High-throughput

0.484

High

490315

RMLB1
dTDP-glucose 4,6-dehydratase 1

1

1

High-throughput

0.484

High

490290

RECA
Protein RecA

1

2

High-throughput

0.479

High

490287

GREA
Transcription elongation factor GreA

1

0

High-throughput

0.464

High

490293

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.464

High

490289

MSRB
Peptide methionine sulfoxide reductase MsrB

1

1

High-throughput

0.457

High

490292

RL29
Large ribosomal subunit protein uL29

1

1

High-throughput

0.442

High

490309

EFTU1
Elongation factor Tu 1

1

9

High-throughput

0.407

High

490310

EFTU2
Elongation factor Tu 2

1

9

High-throughput

0.407

High

490297

SLYB
Outer membrane lipoprotein SlyB

1

0

High-throughput

0.279

Low

490314

INAA
Protein InaA

1

0

High-throughput

0.279

Low

490317

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025