HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: NDF1 (Q13562)
Neurogenic differentiation factor 1 (NeuroD) (NeuroD1) (Class A basic helix-loop-helix protein 3) (bHLHa3)
Gene: NEUROD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	12881483, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043065 - positive regulation of apoptotic process
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 356
+	Hs
		791803 HD_HUMAN (1-3142): 0: 5724: 100.00		TWST2_HUMAN (57-169): 2.72e-29: 112: 33.90
+	Hs
		791585 HD_HUMAN (1-3142): 0: 5724: 100.00		TWST1_HUMAN (11-175): 1.03e-26: 106: 24.18