HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	39079530
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0008289 - lipid binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 708
+	Hs
		791485 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		RUFY3_HUMAN (109-527): 1.6e-33: 136: 56.33
+	Hs
		772650 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		MYH9_HUMAN (72-521): 1.46e-18: 93.1: 11.38
+	Hs
		773113 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		MYH10_HUMAN (392-691): 8.57e-12: 71.2: 10.75
+	Hs
		791879 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		MRCKB_HUMAN (83-458): 2.33e-11: 69.4: 14.78
+	Hs
		791523 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		WDFY3_HUMAN (639-696): 1.26e-10: 67.4: 43.33
+	Hs
		587579 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		DESP_HUMAN (328-650): 9.95e-10: 64.5: 13.41