Protein: RUFY3
Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar)

Gene: RUFY3
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q7L099

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007015 - actin filament organization
GO:0007399 - nervous system development
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1270817

RUFY1
RUN and FYVE domain-containing protein 1

3

16

High-throughput

0.861

High

1270813

RUFY2
RUN and FYVE domain-containing protein 2

2

17

High-throughput

0.811

High

1270827

ARL8B
ADP-ribosylation factor-like protein 8B

2

14

High-throughput

0.768

High

901893

RAB9A
Ras-related protein Rab-9A

2

20

High-throughput

0.754

High

1120110

RB33A
Ras-related protein Rab-33A

2

8

High-throughput

0.700

High

1270828

TRM9B
Probable tRNA methyltransferase 9B

3

0

High-throughput

0.638

High

601345

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

901335

RAB7A
Ras-related protein Rab-7a

1

18

High-throughput

0.618

High

956357

RAB2A
Ras-related protein Rab-2A

1

11

High-throughput

0.618

High

1270814

ARL8A
ADP-ribosylation factor-like protein 8A

1

8

High-throughput

0.618

High

635084

CAN3
Calpain-3

2

4

High-throughput

0.606

High

1270829

ABI3
ABI gene family member 3

2

9

High-throughput

0.606

High

1270815

GL1D1
Glycosyltransferase 1 domain-containing protein 1

2

0

High-throughput

0.602

High

1226455

DCA15
DDB1- and CUL4-associated factor 15

2

1

High-throughput

0.558

High

249157

DSCAM
Cell adhesion molecule DSCAM

1

4

High-throughput

0.541

High

300664

KRT37
Keratin, type I cuticular Ha7

1

17

High-throughput

0.536

High

530005

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.536

High

1129958

MELK
Maternal embryonic leucine zipper kinase

1

5

High-throughput

0.536

High

1270811

KI18B
Kinesin-like protein KIF18B

1

5

High-throughput

0.536

High

1270819

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

13

High-throughput

0.536

High

1270821

DHX33
ATP-dependent RNA helicase DHX33

1

2

High-throughput

0.536

High

1270822

ASB8
Ankyrin repeat and SOCS box protein 8

1

7

High-throughput

0.536

High

1105142

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

903190

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

6

High-throughput

0.515

High

1131297

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.513

High

1270818

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.513

High

1270823

PDE7B
3',5'-cyclic-AMP phosphodiesterase 7B

1

0

High-throughput

0.513

High

1270833

BACE2
Beta-secretase 2

1

0

High-throughput

0.513

High

422414

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

1270810

PRUN1
Exopolyphosphatase PRUNE1

1

0

High-throughput

0.493

High

1270812

KT222
Keratin-like protein KRT222

1

19

High-throughput

0.489

High

1270820

MTG2
Mitochondrial ribosome-associated GTPase 2

1

2

High-throughput

0.489

High

412144

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.479

High

475612

K1C19
Keratin, type I cytoskeletal 19

1

6

High-throughput

0.479

High

562166

LAMP2
Lysosome-associated membrane glycoprotein 2

1

10

High-throughput

0.479

High

791485

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

904317

BRCA2
Breast cancer type 2 susceptibility protein

1

1

Small-scale

0.479

High

1113503

CUL3
Cullin-3

1

10

High-throughput

0.479

High

1156530

CCDC6
Coiled-coil domain-containing protein 6

1

18

High-throughput

0.479

High

1254368

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1270824

NGB
Neuroglobin

1

3

High-throughput

0.479

High

1270826

SMC4
Structural maintenance of chromosomes protein 4

1

9

High-throughput

0.479

High

1270830

CT2NL
CTTNBP2 N-terminal-like protein

1

17

High-throughput

0.479

High

1270825

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.457

High

934783

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

1270816

CEP63
Centrosomal protein of 63 kDa

1

17

High-throughput

0.445

High

1270832

ITM2B
Integral membrane protein 2B

1

5

High-throughput

0.445

High

106163

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

589000

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

695787

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

1031428

IFM3
Interferon-induced transmembrane protein 3

1

9

High-throughput

0.437

High

1233301

LTOR1
Ragulator complex protein LAMTOR1

1

7

High-throughput

0.437

High

1241891

FBX42
F-box only protein 42

1

8

High-throughput

0.437

High

1270831

LAMP3
Lysosome-associated membrane glycoprotein 3

1

9

High-throughput

0.437

High

946245

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

0

High-throughput

0.279

Low

1179803

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1259047

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025