Interactor 1: NKX21 (P43699)
Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP)
Gene: NKX2-1

Interactor 2: PAX8 (Q06710)
Paired box protein Pax-8
Gene: PAX8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 12441357
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 371
Hs

1 450
+ Rn
+ Mm
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024