HitPredict

Interactor 1: CSN1 (P45432)
COP9 signalosome complex subunit 1 (CSN complex subunit 1) (Constitutive photomorphogenesis protein 11) (Protein FUSCA 6)
Gene: CSN1

Interactor 2: CSN2 (Q8W207)
COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Protein FUSCA 12)
Gene: CSN2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.762

Property	Details
Experiments	12615944, 11854419
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PCI~PCI, PCI~RPN7
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 441 At			1 439
+	Mm
		102346 G3UXW9_MOUSE (28-440): 4.8e-105: 323: 45.64		CSN2_MOUSE (6-437): 5.1e-117: 350: 61.34
+	Hs
		897237 CSN1_HUMAN (28-440): 1.81e-100: 310: 45.00		CSN2_HUMAN (6-437): 5.1e-117: 350: 61.34
+	At
		799481 CSN1_ARATH (1-441): 7.1e-135: 396: 100.00		PSD11_ARATH (36-438): 6.5e-82: 260: 18.83
+	An
		1124315 CSN1_EMENI (6-436): 1.48e-98: 305: 35.62		CSN2_EMENI (4-433): 3.95e-105: 322: 48.50
+	Hs
		121764 PSMD6_HUMAN (32-428): 2.95e-109: 329: 19.35		PSD11_HUMAN (29-438): 1.12e-90: 282: 18.62
+	Dm
		1180710 PSMD6_DROME (31-428): 1.38e-101: 309: 17.54		PSD11_DROME (30-438): 6.75e-86: 270: 18.57
+	Hs
		122017 PSMD6_HUMAN (32-428): 2.95e-109: 329: 19.35		PSD12_HUMAN (33-438): 6.2e-74: 240: 14.55
+	Ce
		136317 CSN1_CAEEL (13-440): 4.45e-80: 260: 24.69		CSN2_CAEEL (11-413): 2.46e-99: 307: 53.32
+	Hs
		1024151 CSN1_HUMAN (28-440): 1.81e-100: 310: 45.00		CSN1_HUMAN (11-438): 2.1e-79: 255: 13.20
+	Hs
		1062809 PSMD6_HUMAN (32-428): 2.95e-109: 329: 19.35		PSMD6_HUMAN (39-435): 1.07e-72: 235: 11.39
+	At
		799468 CSN1_ARATH (1-441): 7.1e-135: 396: 100.00		CSN1_ARATH (227-427): 4.16e-43: 158: 17.59
+	Hs
		1024211 CSN1_HUMAN (28-440): 1.81e-100: 310: 45.00		CSN4_HUMAN (67-436): 7.6e-73: 236: 16.17
+	Mm
		102342 G3UXW9_MOUSE (28-440): 4.8e-105: 323: 45.64		CSN4_MOUSE (65-436): 2.96e-67: 221: 16.08
+	Zm
		6700 A0A1D6E9U1_MAIZE (60-431): 3.24e-85: 269: 13.98		A0A1D6E9U1_MAIZE (33-438): 2.26e-87: 274: 19.18
+	At
		799471 CSN1_ARATH (1-441): 7.1e-135: 396: 100.00		CSN4_ARATH (88-436): 6.79e-38: 143: 15.24
+	Sp
		1013798 RPN7_SCHPO (49-421): 2.61e-87: 273: 18.25		RPN6_SCHPO (33-436): 3.38e-79: 253: 18.20
+	At
		1338954 PSD11_ARATH (18-431): 1.02e-82: 262: 13.04		PSD11_ARATH (36-438): 6.5e-82: 260: 18.83
+	Sc
		1015535 RPN6_YEAST (66-429): 1.84e-85: 270: 14.44		RPN6_YEAST (27-438): 1.97e-72: 236: 17.54
+	An
		1124336 CSN1_EMENI (6-436): 1.48e-98: 305: 35.62		CSN4_EMENI (55-434): 1.45e-25: 109: 14.61