HitPredict

Interactor 1: MED31 (P38633)
Mediator of RNA polymerase II transcription subunit 31 (Hpr1 suppressor protein 1) (Mediator complex subunit 31)
Gene: SOH1

Interactor 2: SSN3 (P39073)
Meiotic mRNA stability protein kinase SSN3 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin-dependent kinase 8) (Suppressor of RNA polymerase B SRB10)
Gene: SSN3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016592 - mediator complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 127 Sc			1 555
+	Hs
		897436 MED31_HUMAN (14-95): 7.65e-35: 118: 42.17		CDK7_HUMAN (151-505): 2.89e-126: 375: 29.58
+	Hs
		1416413 MED31_HUMAN (14-95): 7.65e-35: 118: 42.17		CDK19_HUMAN (152-499): 7.88e-108: 333: 40.16
+	Dm
		1302896 MED31_DROME (22-95): 3.04e-35: 122: 44.00		CDK8_DROME (157-500): 7.22e-106: 327: 40.06
+	Hs
		881632 MED31_HUMAN (14-95): 7.65e-35: 118: 42.17		CDK8_HUMAN (191-528): 1.41e-107: 331: 40.90