HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: NAV2 (Q8IVL1)
Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2)
Gene: NAV2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3256 Hs			1 2488
+	Hs
		801013 KI67_HUMAN (1-3256): 0: 1046: 100.00		UTRN_HUMAN (63-355): 2.48e-55: 217: 15.76
+	Hs
		211525 KI67_HUMAN (1-3256): 0: 1046: 100.00		ACTN4_HUMAN (84-187): 4.26e-30: 132: 29.81
+	Hs
		261264 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		FLNB_HUMAN (70-1944): 5.47e-122: 435: 9.92
+	Hs
		598120 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		FLNA_HUMAN (64-1900): 4.31e-116: 416: 10.76
+	Hs
		597999 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		FLNA_HUMAN (64-1900): 4.31e-116: 416: 10.76
+	Hs
		944680 MAP1A_HUMAN (139-2564): 8.72e-104: 377: 10.33		PLEC_HUMAN (2-322): 2.96e-74: 279: 15.46
+	Hs
		598253 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		FLNA_HUMAN (64-1900): 4.31e-116: 416: 10.76
+	Hs
		598171 NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83		FLNA_HUMAN (64-1900): 4.31e-116: 416: 10.76
+	Ce
		184367 O17084_CAEEL (145-2515): 2.28e-49: 198: 7.97		Q23158_CAEEL (52-289): 2.92e-71: 261: 18.40
+	Dm
		1376672 FUTSC_DROME (52-3253): 3.26e-81: 303: 9.16		FUTSC_DROME (225-1996): 1.29e-16: 89.5: 11.58
+	Hs
		1068702 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		PLEC_HUMAN (2-322): 2.96e-74: 279: 15.46
+	Hs
		521586 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		ACTN1_HUMAN (60-309): 3.46e-72: 264: 17.12
+	Hs
		993278 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		ACTN3_HUMAN (46-318): 6.78e-71: 260: 15.00
+	Hs
		963451 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		SPTB2_HUMAN (60-303): 5.64e-57: 222: 16.80
+	Hs
		725681 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		ACTN2_HUMAN (84-187): 9.64e-31: 134: 27.89
+	Hs
		211629 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		ACTN4_HUMAN (84-187): 4.26e-30: 132: 29.81
+	Dm
		574825 TITIN_DROME (757-3249): 1.04e-11: 74: 12.72		ACTN_DROME (84-187): 6.59e-30: 132: 29.81
+	Dm
		113976 M9PB30_DROME (2247-3103): 1.53e-18: 96.6: 7.31		M9PB30_DROME (510-1394): 6.84e-12: 74.1: 11.71
+	Dm
		65570 A8JNM5_DROME (676-2679): 9.04e-14: 80.5: 13.97		FUTSC_DROME (225-1996): 1.29e-16: 89.5: 11.58
+	Hs
		1303336 MUC4_HUMAN (409-3101): 1.78e-16: 89.4: 12.06		MUC4_HUMAN (605-2030): 3.49e-12: 74.8: 11.21