HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 445
+	Hs
		802589 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428080 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		802593 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		548704 VAV_HUMAN (11-189): 6.6e-47: 170: 28.21		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428001 VAV_HUMAN (11-189): 6.6e-47: 170: 28.21		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		548681 VAV_HUMAN (11-189): 6.6e-47: 170: 28.21		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		381112 VAV_HUMAN (11-189): 6.6e-47: 170: 28.21		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		924548 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428131 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		924460 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		924836 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TBB6_HUMAN (1-432): 0: 706: 92.36