HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 783
+	Hs
		802862 CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1167807 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172216 VAV3_HUMAN (11-189): 1.56e-33: 131: 26.15		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		855804 VAV2_HUMAN (2-191): 3.44e-29: 119: 19.74		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		581017 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		924655 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172445 CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1078848 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		802841 CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		275202 GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17		TRI68_HUMAN (200-776): 1.52e-87: 286: 13.42
+	Hs
		581005 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		1078906 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		557686 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		802736 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		802597 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		924879 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Mm
		1143604 PLCG2_MOUSE (11-301): 1.34e-25: 108: 16.40		TRI27_MOUSE (105-456): 7.29e-11: 67.4: 14.77
+	Hs
		536781 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		584954 GRAP_HUMAN (135-294): 3.79e-21: 91.4: 16.67		RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81
+	Hs
		208986 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77