Interactor 1: IF2M (P46199)
Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))
Gene: MTIF2

Interactor 2: GUF1 (Q8N442)
Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)
Gene: GUF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32877691
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EFG_C~GTP_EFTU, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU~LepA_C, GTP_EFTU~IF-2, GTP_EFTU_D2~IF-2
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 727
Hs

1 669
+ Hs
+ Hs
+ Ec
+ Hs
+ Hs
+ Hs
+ Ec
+ Ec
+ Hv
+ Ec
+ Hv

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Last updated: 15 Jul 2024