Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: SIRPD (Q9H106)
Signal-regulatory protein delta (SIRP-delta) (Protein tyrosine phosphatase non-receptor type substrate 1-like 2)
Gene: SIRPD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~V-set, Ank_4~V-set, EGF~V-set, NOD~V-set, NODP~V-set, Notch~V-set
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 197
+ Hs
+ Hs

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Last updated: 15 Jul 2024