Protein: THO2
THO complex subunit 2 (Low dye-binding protein 5) (THO complex subunit RLR1) (Zinc-regulated gene 13 protein)

Gene: THO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P53552

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0000446 - nucleoplasmic THO complex
GO:0000781 - chromosome, telomeric region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921188

TEX1
Protein TEX1

7

15

Small-scale

0.962

High

605914

HPR1
THO complex subunit HPR1

17

0

Small-scale

0.936

High

150183

THP2
THO complex subunit THP2

11

0

Small-scale

0.926

High

753256

MFT1
THO complex subunit MFT1

10

0

Small-scale

0.926

High

921198

SUB2
ATP-dependent RNA helicase SUB2

4

9

Small-scale

0.892

High

921186

THO2
THO complex subunit 2

2

6

Small-scale

0.776

High

676754

GBP2
Serine/arginine

6

5

Small-scale

0.732

High

807683

HRB1
Serine/arginine

4

5

Small-scale

0.691

High

921203

YRA1
RNA annealing protein YRA1

4

6

Small-scale

0.691

High

757510

NCBP1
Nuclear cap-binding protein complex subunit 1

4

1

Small-scale

0.678

High

921199

ULS1
ATP-dependent helicase ULS1

1

5

High-throughput

0.665

High

921194

IMA1
Importin subunit alpha

3

5

High-throughput

0.662

High

792168

GBLP
Small ribosomal subunit protein RACK1

1

14

High-throughput

0.618

High

921196

IMB1
Importin subunit beta-1

2

1

High-throughput

0.612

High

594491

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

2

Small-scale

0.584

High

738890

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

1

Small-scale

0.584

High

921201

NCBP2
Nuclear cap-binding protein subunit 2

2

4

Small-scale

0.584

High

527300

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

545742

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

727212

HS104
Heat shock protein 104

1

1

High-throughput

0.536

High

656562

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.513

High

416558

HXKB
Hexokinase-2

1

0

High-throughput

0.493

High

403601

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

5

Small-scale

0.479

High

435254

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

442034

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

534290

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

1

Small-scale

0.479

High

646484

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

921187

PAP2
Poly(A) RNA polymerase protein 2

1

2

Small-scale

0.479

High

921191

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

921192

NOP3
Serine/arginine

1

16

Small-scale

0.479

High

921195

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

921205

SMC6
Structural maintenance of chromosomes protein 6

1

15

High-throughput

0.479

High

921206

MEX67
mRNA export factor MEX67

1

2

High-throughput

0.479

High

707774

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735085

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

802298

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

858345

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

921202

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

481704

HSP73
Heat shock protein SSA3

1

8

High-throughput

0.445

High

518087

SSBP1
Single-stranded nucleic acid-binding protein

1

5

High-throughput

0.445

High

524701

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

676216

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

742082

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

742910

HSP79
Heat shock protein homolog SSE2

1

10

High-throughput

0.445

High

804338

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

811480

XDJ1
DnaJ protein homolog XDJ1

1

4

High-throughput

0.445

High

383817

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

433763

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

455182

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

504335

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

512565

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

747496

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

510691

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.407

High

577184

SEC63
Protein translocation protein SEC63

1

5

High-throughput

0.407

High

579814

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.407

High

752564

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

871437

HLJ1
Protein HLJ1

1

6

High-throughput

0.407

High

921189

JJJ1
J protein JJJ1

1

5

High-throughput

0.407

High

921197

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.407

High

818127

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.265

Low

149880

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

410254

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

436082

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

503161

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

513133

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514754

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

533495

TIR1
Cold shock-induced protein TIR1

1

0

High-throughput

0.249

Low

577013

CBP7
Cytochrome B translational activator CBS2

1

0

High-throughput

0.249

Low

674748

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

753500

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

778457

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

812524

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

813735

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

0

Small-scale

0.249

Low

874442

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

921190

YNO0
Uncharacterized protein YNL140C

1

0

High-throughput

0.249

Low

921193

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

921200

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

921204

AIR2
Protein AIR2

1

0

Small-scale

0.249

Low

863675

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025